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About ALTACE® > Clinical Studies
Clinical Studies of ALTACE

Clinical Studies

ALTACE® has a respected body of clinical evidence. These studies have great value to the healthcare professionals who prescribe ALTACE® and to the patients who rely on it. It is the value of the only ACE inhibitor proven to reduce the risk of heart attack or stroke in high-risk patients aged 55 or older.1,27,28

The Heart Outcomes Prevention Evaluation (HOPE) Study

HOPE is considered a landmark study by doctors. It was an international study of more than 9,000 patients aged 55 or older who were at high risk for having cardiovascular events.29 HOPE studied the effect of ALTACE® on outcomes such as heart attack, stroke, and death from cardiovascular causes. Learn about the HOPE study.

The Clinical ALTACE® Real-World Efficacy (CARE) Study

CARE was an 8-week study that followed up with 11,100 patients who had mild-to-moderate hypertension to see how ALTACE® changed their blood pressure.32 Learn about the CARE study.

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Talk To Your Healthcare Professional About ALTACE

Talk With Your Healthcare Professional About ALTACE®

Preparing for the conversation can help you feel more comfortable. We created a guide to help your discussion with your healthcare professional.


The quotes presented on this Web site are representative and may not reflect actual patient experience.

Important Safety Information

Do not take ALTACE® during pregnancy, as death or injury to your unborn child may result. Do not take ALTACE® if you have experienced serious side effects related to previous ACE inhibitors.

Common side effects include persistent dry cough, dizziness, and light-headedness due to low blood pressure. Prescription ALTACE® is not for everyone. ALTACE® may cause swelling of the mouth, tongue, or throat, which could cause extremely serious risk and requires immediate medical care. There have been rare reports of low blood sugar in patients taking ALTACE® with medicine for diabetes. Please contact your healthcare professional if you have symptoms of low blood sugar such as sweating or shakiness.

Do NOT take ALTACE® if you are allergic to ALTACE® or other ACE inhibitors.

If you experience side effects that you think may be associated with ALTACE®, talk to your healthcare professional. DO NOT discontinue taking prescribed medication without letting your healthcare professional know.

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