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About ALTACE® > Clinical Studies > The HOPE Study
The HOPE Study

The HOPE Study

In the Heart Outcomes Prevention Evaluation (HOPE) study, ALTACE® reduced the risk of cardiovascular disease for people aged 55 or older who had normal blood pressure or whose high blood pressure was already being treated.29

Key Finding

For the studied group of patients aged 55 or older, ALTACE® reduced the risk of heart attack, stroke, and cardiovascular death beyond other cardiovascular medications taken alone.29 These medications included aspirin, cholesterol-lowering agents, and blood pressure medications.29

HOPE Study Results

The HOPE study proved 10-mg doses of ALTACE® reduced cardiovascular risk in high-risk patients aged 55 or older. ALTACE® reduced the relative risk of heart attack by 20%, cardiovascular death by 26%, and stroke by 32%.29 These results were in addition to the effect of any other medications the patients were already taking.29

HOPE chart

Ask your healthcare professional if ALTACE® is right for you. It can help if you prepare before talking to your healthcare professional about ALTACE®.

More

  • For the effect that ALTACE® has on lowering blood pressure, see the CARE study
  • Preparing to speak with your healthcare professional about your health and ALTACE® will help you have a more satisfying appointment. We prepared this discussion guide so you can share what you have learned

These People Used ALTACE® to Lower Their Cardiovascular Risk in the HOPE Study

The HOPE study focused on people who were aged 55 or older who had either29

  • Diabetes plus another risk factor such as high blood pressure, high cholesterol, a habit of cigarette smoking, or protein in the urine
  • A history of coronary artery disease, stroke, or peripheral vascular disease

The quotes presented on this Web site are representative and may not reflect actual patient experience.

Important Safety Information

Do not take ALTACE® during pregnancy, as death or injury to your unborn child may result. Do not take ALTACE® if you have experienced serious side effects related to previous ACE inhibitors.

Common side effects include persistent dry cough, dizziness, and light-headedness due to low blood pressure. Prescription ALTACE® is not for everyone. ALTACE® may cause swelling of the mouth, tongue, or throat, which could cause extremely serious risk and requires immediate medical care. There have been rare reports of low blood sugar in patients taking ALTACE® with medicine for diabetes. Please contact your healthcare professional if you have symptoms of low blood sugar such as sweating or shakiness.

Do NOT take ALTACE® if you are allergic to ALTACE® or other ACE inhibitors.

If you experience side effects that you think may be associated with ALTACE®, talk to your healthcare professional. DO NOT discontinue taking prescribed medication without letting your healthcare professional know.

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